I was diagnosed with dyslexia when I was ten. At the time I was told that I had built coping mechanisms and there was nothing to do. Which is fine. But long duration reading is still painful for me.
Recently a new font, Open Dyslexic, was released, and for me it actually helps. So I wrote a tiny little Google Chrome extension that adds a CSS definition to the current tab to turn the ‘default’ font for the page to Open Dyslexic.